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Current experiments are directed at the molecular identification of mesoderm-derived inducing signals at different rostro-caudal levels and the characterization of the response of neuroepithelial cells to such signals.
The lab is developing methods that temporally extend genetic access to this specific population of neurons and permit identification and manipulation of dI1 specific circuits from DRG to brain, using state of the art trans-synaptic viral tracers and gene discovery.
Visualizing the synaptic connections between dI1 cells and specific functional classes of dorsal root ganglion DRG neurons, identifying central targets and the axonal routes of these neurons, and eventually manipulating their activities, will provide novel insights into the functional organization of somatosensory circuits in the developing spinal cord.
Visual System. Somatosensory System. Current Members. Lab Alumni. Lab News. General Lab Guidelines.
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